Field research trials were conducted during the 2020 growing season at different locations in Kentucky. One trial’s objective was to evaluate the effect of nematicide seed treatments on soybean cyst nematode (SCN) reproduction and soybean yield, and the other trial’s objective was to determine the best foliar fungicide management programs for control of target spot and frogeye leaf spot. For the nematicide seed treatment trial, two locations had moderate to high levels of soybean cyst nematode (9,335 to 12,283 SCN eggs/100 cc soil). Despite the high SCN populations at these locations, no statistically significant differences were observed among treatments for plant stand, soybean yield, or SCN reproduction. For the target spot foliar fungicide trial, fungicide treatments that provided the greatest target spot control were Lucento, Miravis Top, Revytek, and Priaxor + Tilt (Fig. 1). No statistically significant differences in yield were observed for this trial. For the frogeye leaf spot foliar fungicide trial in Breathitt County, KY, fungicide treatments that provided the greatest frogeye leaf spot control were Acropolis, Froghorn, Topsin, and Miravis Top (Fig. 2). No statistically significant differences in yield were observed for this trial. For the frogeye leaf spot foliar fungicide trial in Union County, KY, fungicide treatments that provided the greatest frogeye leaf spot control were Miravis Top, Revytek, and Lucento (Fig. 3). No statistically significant differences in yield were observed for this trial. The results of these trials will help Kentucky soybean farmers make better disease management decisions.